Modeling Self-organization of Microtubules from Tubulins
2: Virginia Commonwealth University
Self-assembly is a ubiquitous, naturally occurring, robust process in many living organisms. Microtubules are a well-studied type of natural self-organization systems that assemble into functional units by attaching to cellular structures. Modeling microtubule self-organization is of broad interest as they form a network of protein filaments that is critical to many processes in eukaryotic cells. In this paper, we propose a modeling algorithm starting from alpha and beta tubulins as basic building blocks in the self-organization of microtubules. The preliminary results obtained from our algorithm demonstrate that such self-organization stems from the properties of the basic building blocks that can be used to form the complex microtubule structures.
- Published: 2nd Feb 2015
- Publisher: ACM